2-(1,3-Dioxaindan-5-yl)ethan-1-ol → N-{4-[2-(1,3-Benzodioxol-5-yl)ethoxy]benzoyl}glycine

Participants

Reaction Steps

The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (300 mg, 1.19 mmol) prepared in Example 1 (1a) and 2-(1,3-benzodioxol-5-yl)ethanol (which is the compound disclosed in Tetrahedron, (2003), 59, 3369-3378, 239 mg, 1.44 mmol) to give 356 mg of the title compound (pale red powder, yield: 87%).

Provenance & Evidence