N-(4-Hydroxybenzoyl)glycine tert-butyl ester → N-[4-(2-Cyclopenta-2-en-1-ylethoxy)benzoyl]glycine

Participants

Reaction Steps

The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (157 mg, 0.625 mmol) prepared in Example 1 (1a) and 2-cyclopenta-2-en-1-ylethanol (which is the compound disclosed in J. Org. Chem., (2000), 65, 4241-4250, 85 mg, 0.75 mmol) to give 128 mg of the title compound (white powder, yield: 72%).

Provenance & Evidence