HRID1099595

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O$

HCID5280581

(8Z,11Z,14Z)-8,11,14-Eicosatrienoic acid

C20H34O2

$结构：CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O$

HCID5280933

Gamolenic acid

C18H30O2

$结构：CC/C=C\C/C=C\C/C=C\C/C=C\CCCCC(=O)O$

HCID5312508

(6Z,9Z,12Z,15Z)-Octadecatetraenoic acid

C18H28O2

PRODUCTS

生成物

$结构：CCCCCCCC/C=C\CCCCCCCC(=O)O$

HCID445639

Oleic acid

C18H34O2

$结构：CCCCC/C=C\C/C=C\CCCCCCCC(=O)O$

HCID5280450

Linoleic acid

C18H32O2

PROCEDURE

实验过程

A number of enzymes are involved in PUFA biosynthesis in addition to Δ5-desaturase and Δ6-desaturase. For example, elongase (elo) catalyzes the conversion of γ-linolenic acid (GLA) to dihomo-γ-linolenic acid (DGLA) and of stearidonic acid (18:4n-3) to (n-3)-eicosatetraenoic acid (20:4n-3). Linoleic acid (LA, 18:2-Δ9,12 or 18:2n-6) is produced from oleic acid (18:1-Δ9) by a Δ12-desaturase. GLA (18:3-Δ6,9,12) is produced from linoleic acid by a Δ6-desaturase.

WORKUP

后处理

additionin addition to Δ5-desaturase and Δ6-desaturase

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bedf340c600048ada65056f26a7f2a43
来源数据集: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08143486B2
来源说明: uspto-grants-2012_03

反应 SMILES

[C:1]([OH:20])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5]/[CH:6]=[CH:7]\[CH2:8]/[CH:9]=[CH:10]\[CH2:11]/[CH:12]=[CH:13]\[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].CC[CH2:23][CH2:24][CH2:25]/[CH:26]=[CH:27]\[CH2:28]/[CH:29]=[CH:30]\[CH2:31]/[CH:32]=[CH:33]\[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][C:40]([OH:42])=[O:41].C(O)(=O)CCCC/C=C\C/C=C\C/C=C\C/C=C\CC>>[C:1]([OH:20])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]/[CH:9]=[CH:10]\[CH2:11]/[CH:12]=[CH:13]\[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[C:40]([OH:42])(=[O:41])[CH2:39][CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]/[CH:32]=[CH:31]\[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH3:23]