HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Iodophenyl)ethan-1-one → (s)-5-[(4-Acetylphenyl)ethynyl]-n-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Iodophenyl)ethan-1-one | HCID 72869 | — |
| Reactant | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| Product | (s)-5-[(4-Acetylphenyl)ethynyl]-n-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953842 | 86% |
Reaction Steps
In a manner similar to that describe in Example 434 a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 4-iodoacetophenone were reacted to give the title compound as a light yellow foam (52 mg, 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143410B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-5b8322cd612e49ebbc2d84a5226147a9 |
| Source note | uspto-grants-2012_03 |