HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-iodo-1H-imidazole → (S)-5-(1H-imidazol-2-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-iodo-1H-imidazole | HCID 2773468 | — |
| Reactant | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| Product | (S)-5-(1H-imidazol-2-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 86629468 | 29% |
Reaction Steps
In a manner similar to that describe in Example 434, a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 2-iodo-1H-imidazole were reacted to give the title compound as a white solid (15 mg, 29%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08143410B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-e4094687fd1447faa4a98fc6db636ecd |
| Source note | uspto-grants-2012_03 |