HRID1099688

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)c1cccc(S(C)(=O)=NC(=O)c2cncc(Br)c2)c1

HCID57657891

未命名化合物

HCID57657904

未命名化合物

PRODUCTS

生成物

结构：COC(=O)c1cccc(S(C)(=O)=NC(=O)c2cncc(C#Cc3cccc(NC(=O)c4cc(C)nn4C)c3)c2)c1

HCID57657956

未命名化合物

PROCEDURE

实验过程

In a manner similar to that described in Example 460, methyl 3-{N-[(5-bromopyridin-3-yl)carbonyl]-S-methylsulfonimidoyl}benzoate and N-(3-ethynylphenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide were reacted to give the title compound.

WORKUP

后处理

customwere reacted

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-97d315e8d8f941bba184293b748b6f1d
来源数据集: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08143410B2
来源说明: uspto-grants-2012_03

反应 SMILES

Br[C:2]1[CH:3]=[C:4]([C:8]([N:10]=[S:11]([C:14]2[CH:15]=[C:16]([CH:21]=[CH:22][CH:23]=2)[C:17]([O:19][CH3:20])=[O:18])([CH3:13])=[O:12])=[O:9])[CH:5]=[N:6][CH:7]=1.[C:24]([C:26]1[CH:27]=[C:28]([NH:32][C:33]([C:35]2[N:39]([CH3:40])[N:38]=[C:37]([CH3:41])[CH:36]=2)=[O:34])[CH:29]=[CH:30][CH:31]=1)#[CH:25]>>[CH3:40][N:39]1[C:35]([C:33]([NH:32][C:28]2[CH:27]=[C:26]([C:24]#[C:25][C:2]3[CH:3]=[C:4]([C:8]([N:10]=[S:11]([C:14]4[CH:15]=[C:16]([CH:21]=[CH:22][CH:23]=4)[C:17]([O:19][CH3:20])=[O:18])([CH3:13])=[O:12])=[O:9])[CH:5]=[N:6][CH:7]=3)[CH:31]=[CH:30][CH:29]=2)=[O:34])=[CH:36][C:37]([CH3:41])=[N:38]1