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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1099692Generated: October 30, 2026

5-Bromonicotinic acid → 5-((3-(3-Methylfuran-2-carboxamido)phenyl)ethynyl)nicotinic acid

https://huagongshe.com/reaction/1099692

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromonicotinic acidHCID 88707—
ReactantN-(3-ethynylphenyl)-3-methylfuran-2-carboxamideHCID 51337833—
Product5-((3-(3-Methylfuran-2-carboxamido)phenyl)ethynyl)nicotinic acidHCID 57657847—

Reaction Steps

In a manner similar to that described for Example 480 (step 1), 3-methyl-furan-2-carboxylic acid (3-ethynyl-phenyl)-amide and 5-bromo nicotinic acid were reacted to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08143410B2
Source datasetuspto-grants-2012_03
ORD IDord-3d830779e0b04195992936e4d964e107
Source noteuspto-grants-2012_03