HRID1099701

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=c1oc2c(Cl)cccc2cc1S(=O)(=O)Nc1ccc(Br)cc1

HCID10047436

未命名化合物

2 次

PRODUCTS

生成物

结构：COc1ccc(NS(=O)(=O)c2cc3cc(Br)ccc3oc2=O)cc1

HCID11647209

未命名化合物

PROCEDURE

实验过程

6-chloro-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide; 8-ethoxy-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide; 6-chloro-N-(3-hydroxy-4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide; N-(3-amino-4-fluorophenyl)-8-ethoxy-2-oxo-2H-chromene-3-sulfonamide; N-(3-amino-4-fluorophenyl)-6-methoxy-2-oxo-2H-chromene-3-sulfonamide; N-(4-bromophenyl)-6-methoxy-2-oxo-2H-chromene-3-sulfonamide; 8-ethoxy-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide; N-(4-bromophenyl)-8-chloro-2-oxo-2H-chromene-3-sulfonamide; N-(4-bromophenyl)-8-bromo-2-oxo-2H-chromene-3- sulfonamide; mixtures thereof; and salts thereof.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-af119e5a5ed44865af0731d844878cd1
来源数据集: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08143428B2
来源说明: uspto-grants-2012_03

反应 SMILES

Cl[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[O:8][C:7](=[O:12])[C:6]([S:13]([NH:16][C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1)(=[O:15])=[O:14])=[CH:5]2.C(OC1C=CC=C2C=1OC(=O)C(S(NC1C=CC(OC)=CC=1)(=O)=O)=C2)C.ClC1C=C2C(=CC=1)OC(=O)C(S(NC1C=CC(OC)=C(O)C=1)(=O)=O)=C2.NC1C=C(NS(C2C(=O)OC3C(C=2)=CC=CC=3OCC)(=O)=O)C=CC=1F.NC1C=C(NS(C2C(=O)OC3C(C=2)=CC(OC)=CC=3)(=O)=O)C=CC=1F.[Br:127]C1C=CC(NS(C2C(=O)OC3C(C=2)=CC(OC)=CC=3)(=O)=O)=CC=1.BrC1C=CC(NS(C2C(=O)OC3C(C=2)=CC=CC=3Cl)(=O)=O)=CC=1.BrC1C=CC(NS(C2C(=O)OC3C(C=2)=CC=CC=3Br)(=O)=O)=CC=1>>[Br:127][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[O:8][C:7](=[O:12])[C:6]([S:13]([NH:16][C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1)(=[O:15])=[O:14])=[CH:5]2