HCID 66811244, compound → HCID 66811311, compound

HRID 1099703Notes

Reaction equation

HRID 1099703 reaction equation
Cl[C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[C:7]([S:13]([NH:16][C:17]3[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=3)(=[O:15])=[O:14])[C:8](=[O:12])[NH:9]2)=[CH:4][CH:3]=1.BrC1C=C(Br)C=C2C=1C=C(S(NC1C=CC(OC)=CC=1)(=O)=O)C(=O)N2.OC1C=C(C2C3C(=CC=CC=3)NC(=O)C=2S(N)(=O)=O)C=CC=1OC.NC1C=C(NS(C2C(=O)NC3C(C=2)=CC=CC=3)(=O)=O)C=CC=1F.ClC1C=C2C(C=C(S(NC3C=CC(F)=C(N)C=3)(=O)=O)C(=O)N2)=CC=1.BrC1C=C(Br)C=C2C=1C=C(C(NC1C=CC(F)=C(N)C=1)=O)C(=O)N2.BrC1C=CC(NS(C2C(=O)NC3C(C=2)=CC=CC=3)(=O)=O)=CC=1.BrC1C=C(Br)C=C2C=1C=C(S(NC1C=CC(Br)=CC=1)(=O)=O)C(=O)N2>>[CH3:24][O:23][C:20]1[CH:21]=[CH:22][C:17]([NH:16][S:13]([C:7]2[C:8](=[O:12])[NH:9][C:10]3[C:5]([CH:6]=2)=[CH:4][CH:3]=[CH:2][CH:11]=3)(=[O:15])=[O:14])=[CH:18][CH:19]=1

Participants

9

Reactant 8

HCID 66811244HCID 66811244, compoundHCID 66811356HCID 66811356, compoundHCID 66811360HCID 66811360, compoundHCID 66811527HCID 66811527, compoundHCID 66811565HCID 66811565, compoundHCID 66811596HCID 66811596, compoundHCID 66811621HCID 66811621, compoundHCID 86615530HCID 86615530, compound3×

Product 1

HCID 66811311HCID 66811311, compound

Procedure

7-chloro-1,2-dihydro-N-(4-methoxyphenyl)-2-oxoquinoline-3-sulfonamide; 5,7-dibromo-1,2-dihydro-N-(4-methoxyphenyl)-2-oxoquinoline-3-sulfonamide; 1,2-dihydro-N-((3-hydroxy-4-methoxyphenyl)-2-oxoquinoline-3-sulfonamide; 7-chloro-1,2-dihydro-N-((3-hydroxy-4-methoxyphenyl)-2-oxoquinoline-3-sulfonamide; 5,7-dibromo-1,2-dihydro-N-((3-hydroxy-4-methoxyphenyl)-2-oxoquinoline-3-sulfonamide; 1,2-dihydro-N-(3-amino-4-fluorophenyl)-2-oxoquinoline-3-sulfonamide; 7-chloro-1,2-dihydro-N-(3-amino-4-fluorophenyl)-2-oxoquinoline-3-sulfonamide; 5,7-dibromo-1,2-dihydro-N-(3-amino-4-fluorophenyl)-2-oxoquinoline-3-carboxamide; 1,2-dihydro-N-(4-bromophenyl)-2-oxoquinoline-3-sulfonamide; 7-chloro-1,2-dihydro-N-(4-bromophenyl)-2-oxoquinoline-3-sulfonxamide; 5,7-dibromo-1,2-dihydro-N-(4-bromophenyl)-2-oxoquinoline-3-sulfonamide; mixtures thereof; and salts thereof.

Sources & evidence

ORD record
ord-3cb441f5d4ab418da91c01bbad9056bd
Source dataset
uspto-grants-2012_03
Patent number
US08143428B2

Reaction notes

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