2-Hydroxy-5-methoxybenzaldehyde → N-(4-Bromophenyl)-6-methoxy-2-oxo-2H-chromene-3-sulfonamide

HRID 1099711Notes

Reaction equation

HRID 1099711 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[C:7]([CH:8]=O)[C:6]([OH:11])=[CH:5][CH:4]=1.[Br:12][C:13]1[CH:26]=[CH:25][C:16]([NH:17][S:18]([CH2:21][C:22](O)=[O:23])(=[O:20])=[O:19])=[CH:15][CH:14]=1>C(O)(=O)C>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([NH:17][S:18]([C:21]2[C:22](=[O:23])[O:11][C:6]3[C:7]([CH:8]=2)=[CH:10][C:3]([O:2][CH3:1])=[CH:4][CH:5]=3)(=[O:20])=[O:19])=[CH:25][CH:26]=1

Participants

4

Reactant 2

HCID 956952-Hydroxy-5-methoxybenzaldehydeHCID 187723614-Bromoanilinosulfonyl acetic acid

Product 1

HCID 11632918N-(4-Bromophenyl)-6-methoxy-2-oxo-2H-chromene-3-sulfonamide

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 5-methoxysalicylaldehyde (1 mmol) and 4-bromoanilinosulfonyl acetic acid (1 mmol) in acetic acid (10 mL) was subjected to the General Procedure 1, Method A to yield the title compound; m.p. 166-168° C.

Sources & evidence

ORD record
ord-6d1df9928c1642b0b09ef095cf4a9363
Source dataset
uspto-grants-2012_03
Patent number
US08143428B2

Reaction notes

Loading…