O-Ethylvanillin → 8-ethoxy-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide

HRID 1099712Notes

Reaction equation

HRID 1099712 reaction equation
[CH2:1]([O:3][C:4]1[CH:11]=[CH:10][CH:9]=[C:6]([CH:7]=O)[C:5]=1[OH:12])[CH3:2].[CH3:13][O:14][C:15]1[CH:28]=[CH:27][C:18]([NH:19][S:20]([CH2:23][C:24](O)=[O:25])(=[O:22])=[O:21])=[CH:17][CH:16]=1>C(O)(=O)C>[CH2:1]([O:3][C:4]1[CH:11]=[CH:10][CH:9]=[C:6]2[C:5]=1[O:12][C:24](=[O:25])[C:23]([S:20]([NH:19][C:18]1[CH:27]=[CH:28][C:15]([O:14][CH3:13])=[CH:16][CH:17]=1)(=[O:22])=[O:21])=[CH:7]2)[CH3:2]

Participants

4

Reactant 2

HCID 68117O-EthylvanillinHCID 127443134-Methoxyanilinosulfonyl acetic acid

Product 1

HCID 443933958-ethoxy-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 3-ethoxysalicylaldehyde (1 mmol) and 4-methoxyanilinosulfonyl acetic acid (1 mmol) in acetic acid (10 mL) was subjected to the General Procedure 1, Method A to yield the title compound; m.p. 206-209° C.

Sources & evidence

ORD record
ord-7bcf44205cbc41c58800955f10f3ec77
Source dataset
uspto-grants-2012_03
Patent number
US08143428B2

Reaction notes

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