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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1099992Generated: October 29, 2026

6-Chloroquinoline → HCID 178422846, compound

https://huagongshe.com/reaction/1099992

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-ChloroquinolineHCID 69163—
Reactant[5-Methyl-1-(oxan-2-yl)-1H-indazol-4-yl]boronic acidHCID 129009568—
Reagent2-Propanol, 2-methyl-, lithium salt (1:1)HCID 23664764—
Catalystpalladium(II) acetateHCID 167845—
SolventWaterHCID 962—
SolventTolueneHCID 1140—
SolventDimethylformamideHCID 6228—
Solvent1,3,5-TriethylbenzeneHCID 7602—
SolventHexaneHCID 8058—
Solvent1,3-DiethylbenzeneHCID 8864—
ProductHCID 178422846HCID 17842284615.89%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1126/science.aap9112
Source datasetRapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions
ORD IDord-d5ac494d58614e61807be2649adf439d
Source noteRapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions