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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 110201Generated: October 28, 2026

Sodium ion → 6-Chloro-2-(2,2-difluoro-ethoxy)-nicotinonitrile

https://huagongshe.com/reaction/110201

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantAcetonitrileHCID 6342—
ReactantPhosphorus oxychlorideHCID 24813—
Reactant6-Chloro-2-(2,2-difluoro-ethoxy)-nicotinamideHCID 57969008—
Product6-Chloro-2-(2,2-difluoro-ethoxy)-nicotinonitrileHCID 86636458—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-cf234de537f14da9a8ff4b0fc352b350
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)