(2,6-Dimethoxyphenyl)boronic acid → 4-(2,6-dimethoxyphenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

Beteiligte Stoffe

Reaktionsschritte

The reaction of 9-hydroxy-4-iodopyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione, prepared as in example 7, with 2,6-dimethoxybenzeneboronic acid according to the procedure described in example 8 gave 4-(2,6-dimethoxyphenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione (19) (I, Ar=2,6-dimethoxyphenyl) in a 43% yield; mp 275–277° C. (dec). 1H NMR δ [(CD3)2SO] 11.62 (br s, 1H), 10.83 (br s, 1H), 9.21 (br s, 1H), 8.29 (d, J=2.4 Hz, 1H), 7.42 (s, 1H), 7.41 (d, J=8.4 Hz, 1H), 7.35 (t, J=8.4 Hz, 1H), 7.04 (dd, J=8.4, 2.4 Hz, 1H), 6.75 (d, J=8.4 Hz, 2H), 3.63 (s, 6H). Found: C, 66.31; H, 4.50, N, 6.70. C22H16N2O5,1/2H2O requires C, 66.49; H, 4.31; N, 7.04.

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