5-chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiophene-2-sulfonamide → 5-[7-Difluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide
Reaction equation
[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[CH:13])[F:24].[OH:25][CH2:26][C:27]([CH3:28])([CH3:29])[NH:30][S:31](=[O:32])(=[O:33])[c:34]1[s:35][c:36]([Cl:39])[cH:37][cH:38]1>>[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[C:13][c:36]1[s:35][c:34]([S:31]([NH:30][C:27]([CH2:26][OH:25])([CH3:28])[CH3:29])(=[O:32])=[O:33])[cH:38][cH:37]1)[F:24]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ad52e0cd0ac543e28f4c03a422b9ac0a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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