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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1102771Generated: October 30, 2026

6-Chloroquinoline → HCID 178422846, compound

https://huagongshe.com/reaction/1102771

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-ChloroquinolineHCID 69163—
ReactantHCID 134714813HCID 134714813—
Reagent2-Propanol, 2-methyl-, lithium salt (1:1)HCID 23664764—
Catalystpalladium(II) acetateHCID 167845—
Catalyst2-Dicyclohexylphosphino-2',6'-dimethoxybiphenylHCID 11269872—
SolventMethanolHCID 887—
SolventWaterHCID 962—
SolventTolueneHCID 1140—
SolventDimethylformamideHCID 6228—
Solvent1,3,5-TriethylbenzeneHCID 7602—
SolventHexaneHCID 8058—
Solvent1,3-DiethylbenzeneHCID 8864—
ProductHCID 178422846HCID 17842284660.02%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1126/science.aap9112
Source datasetRapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions
ORD IDord-eff639e0e3534822a55bfb0ced6d58d1
Source noteRapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions