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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1104100Generated: October 28, 2026

6-Chloroquinoline → HCID 178422846, compound

https://huagongshe.com/reaction/1104100

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-ChloroquinolineHCID 69163—
ReactantHCID 178422845HCID 178422845—
ReagentSodium BicarbonateHCID 516892—
Catalystpalladium(II) acetateHCID 167845—
CatalystBis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)HCID 11714597—
SolventWaterHCID 962—
SolventTolueneHCID 1140—
SolventDimethylformamideHCID 6228—
Solvent1,3,5-TriethylbenzeneHCID 7602—
SolventTetrahydrofuranHCID 8028—
Solvent1,3-DiethylbenzeneHCID 8864—
ProductHCID 178422846HCID 17842284614.96%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1126/science.aap9112
Source datasetRapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions
ORD IDord-5d29819acc324bfcbcc40ef023c058d9
Source noteRapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions