Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1104264Generated: October 30, 2026

6-Chloroquinoline → HCID 178422846, compound

https://huagongshe.com/reaction/1104264

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-ChloroquinolineHCID 69163—
ReactantHCID 178422845HCID 178422845—
ReagentSodium HydroxideHCID 14798—
Catalystpalladium(II) acetateHCID 167845—
Catalyst1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 636044—
SolventMethanolHCID 887—
SolventWaterHCID 962—
SolventTolueneHCID 1140—
SolventDimethylformamideHCID 6228—
Solvent1,3,5-TriethylbenzeneHCID 7602—
Solvent1,3-DiethylbenzeneHCID 8864—
ProductHCID 178422846HCID 17842284621.68%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1126/science.aap9112
Source datasetRapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions
ORD IDord-432ed7fc069b4955aa08c646aa8a82e6
Source noteRapid material-sparing screening of 5760 Suzuki-Miyaura coupling reactions