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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1105489Generated: October 26, 2026

2-Ethynylpropane-1,2,3-triol → HCID 151299716, compound

https://huagongshe.com/reaction/1105489

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Ethynylpropane-1,2,3-triolHCID 87452564—
ReagentCopper sulfate pentahydrateHCID 24463—
Reagent1,4-Piperazinediethanesulfonic acid, potassium salt (1:2)HCID 176078—
SolventWaterHCID 962—
ProductHCID 151299716HCID 15129971668%

Reaction Conditions

Temperature25 °C
pH7.5

aeration began after addition of copper_sulfate

Provenance & Evidence

DOI10.1126/science.aay8484
Source datasetsynthesis of islatravir by biocatalytic cascade
ORD IDord-9b830b3dea9b4c68b349f901df69e119
Source notesynthesis of islatravir by biocatalytic cascade