反应详情

This was prepared in an identical manner to the compound described in Example 1 using 2-hydroxy-2-(3-chlorophenyl) ethanamine (5.45 g) and 4-{(E)-2-carbomethoxyethenyl}phenylpropan-2-one (7.11 g). The resulting oil was chromatographed on Kieselgel 60. Elution with 5% methanol-chloroform gave the title compound, 9.8 g τ (CDCl3) 8.9 (3H, d, J=6 Hz), 6.8-7.5 (7H, m, 2H disappears with D2O), 6.25 (3H, s), 5.4 (1H, m), 3.6 (1H, d, J=16 Hz), 2.5-2.9 (8H, m), 2.35 (1H, d, J=16 Hz).

1. customThis was prepared in an identical manner to the compound
2. customThe resulting oil was chromatographed on Kieselgel 60
3. washElution with 5% methanol-chloroform