Ethanol → 4-Nitro-1,2-diethyl-pyrazolidine

Participants

Reaction Steps

To a suspension of 3 g. (0.022 moles) potassium carbonate in 20 ml ethanol in an ice bath was added 1.8 g. (0.011 moles) diethyl hydrazine dihydrochloride monohydrate with stirring for about 5 min. To this was added 1.92 (0.011 moles) of 1,3-bis-dimethylamino-2-nitropropane and stirring continued at room temperature for 2.5 hr. The alcoholic solution was decanted from the solid and evaporated to give a dark oil. Diethyl ether was added to give a suspension. Magnesium sulfate was added and the liquid portion separated and evaporated to an oil. Nuclear Magnetic Resonance confirmed presence of the product with some contamination of starting nitro compound.

Provenance & Evidence