2,6-Dichlorobenzoic acid → HCID 86738201, compound

Participants

Reaction Steps

This compound was prepared in the manner of Example I, using 12.2 grams (0.064 mole) of 2,6-dichlorobenzoic acid, 4.2 grams (0.064 mole) of potassium hydroxide, 8.7 grams (0.064 mole) of chloroacetic acid 2,2-dimethylhydrazide, and 1.7 grams of 1,4,7,10,13,16-hexaoxacyclooctadecane in 180 ml of dry toluene. The crude product was recrystallized twice from ethyl acetate using decolorizing carbon to give 18.6 grams of 2,6-dichlorobenzoyloxyacetic acid 2,2-dimethylhydrazide; mp 160°-162°. The ir and the nmr spectra were consistent with the proposed structure.

Provenance & Evidence