Ethanol → HCID 23710471, compound

Participants

Reaction Steps

To a stirred solution of 6.0 grams (0.024 mole) of carboxymethyl 2,6-dichlorobenzoate (the compound of Example X) in 100 ml of ethanol was added a solution of 0.9 gram (0.022 mole) of sodium hydroxide in 50 ml of ethanol. The reaction mixture was stirred for 1.75 hours during which time a solid precipitate formed. The solid was collected by filtration and washed with ethanol. The filtrate was concentrated to a volume of 50 ml, and a second crop of solid was collected by filtration. The solids were combined to give 3.7 grams of sodium 2,6-dichlorobenzoylacetate; mp 241° (decomposes). The nmr and the ir spectra were consistent with the proposed structure.

Provenance & Evidence