HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanebutanoic acid → Cyclohexanebutanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanebutanoic acid | HCID 75200 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Cyclohexanebutanol | HCID 78182 | — |
Reaction Steps
4-cyclohexylbutyric acid (Aldrich) is reduced with excess lithium aluminum hydride in ether to yield 4-cyclohexyl-1-butanol (D. S. Hiers and R. Adams, J. Am. Chem. Soc., 48 2385 (1926)) which is cloro-methylated with hydrogen chloride and formaldehyde to yield the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04310529 |
| Source dataset | uspto-grants-1982_01 |
| ORD ID | ord-a382c8db466747289064245a96a340a1 |
| Source note | uspto-grants-1982_01 |