Sodium Hydroxide → HCID 56631149, compound

HRID 1105847Notes

Reaction equation

HRID 1105847 reaction equation
[CH3:1][C@@H:2]([C@@H:8]1[C@:25]2([CH3:26])[C@H:11]([C@H:12]3[C@H:22]([CH2:23][CH2:24]2)[C@:20]2([CH3:21])[C:15]([CH2:16][C@@H:17]([O:31]C(=O)C)[CH2:18][C@@H:19]2[O:27]C(=O)C)=[CH:14][CH2:13]3)[CH2:10][CH2:9]1)[CH2:3][O:4]C(=O)C.[OH-].[Na+]>CO>[CH3:1][C@@H:2]([C@@H:8]1[C@:25]2([CH3:26])[C@H:11]([C@H:12]3[C@H:22]([CH2:23][CH2:24]2)[C@:20]2([CH3:21])[C:15]([CH2:16][C@@H:17]([OH:31])[CH2:18][C@@H:19]2[OH:27])=[CH:14][CH2:13]3)[CH2:10][CH2:9]1)[CH2:3][OH:4]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 56608691HCID 56608691, compound

Product 1

HCID 56631149HCID 56631149, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of (20S)-20-methyl-1α,3β,21-triacetyloxypregn-5-ene in methanol was treated with sodium hydroxide at reflux to produce (20S)-20-methylpregn-5-ene-1α,3β,21-triol.

Workup

  1. temperatureat reflux

Sources & evidence

ORD record
ord-88523b1ab92c4f1ba0fc26bdd620cbbc
Source dataset
uspto-grants-1982_01
Patent number
US04310467

Reaction notes

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