HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[15-(Trifluoromethyl)pentadecylamino]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 4-[15-(trifluoromethyl)pentadecylamino]benzoate | HCID 12797299 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-[15-(Trifluoromethyl)pentadecylamino]benzoic acid | HCID 12831610 | — |
Reaction Steps
A mixture of 6.0 g. of ethyl 4-[15-(trifluoromethyl)pentadecylamino]benzoate, 4.0 g. of potassium hydroxide and 50 ml. of ethanol is stirred at 80° C. for 4 hours. The mixture is diluted with water and adjusted to pH 5.5 by the addition of concentrated hydrochloric acid. Cooling and filtration affords a solid which is recrystallized from acetone to yield the product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04310545 |
| Source dataset | uspto-grants-1982_01 |
| ORD ID | ord-63a7d254894c46c4a3145c4c135feb64 |
| Source note | uspto-grants-1982_01 |