Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Bromohexadecane | HCID 8213 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Methyl-1,3-benzoxazol-6-ol | HCID 676504 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 12886752 | HCID 12886752 | 100.5% |
Reaction Steps
A mixture composed of 18.0 g of 6-hydroxy-2-methylbenzoxazole synthesized in Synthesis Example 1, 36.6 g of 1-bromohexadecane, 24.0 g of potassium carbonate and 120 ml of N,N-dimethylformamide was stirred at 90° C. for 4.5 hours. Solids were removed from the reacting solution by filtration, and the filtrate was poured into 500 ml of methanol. The crystals formed were separated by filtration to obtain 45.0 g of 6-hexadecyloxy-2-methylbenzoxazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04310693 |
|---|
| Source dataset | uspto-grants-1982_01 |
|---|
| ORD ID | ord-bad29c0d8c2949e7bb5f42b378f70fd5 |
|---|
| Source note | uspto-grants-1982_01 |
|---|
