(+)-Lactose → HCID 131712645, compound

HRID 1106017Notes

Reaction equation

HRID 1106017 reaction equation
[Na+:1].[CH2:2]([NH:18][C:19]1[CH:27]=[CH:26][C:22]([C:23]([O-:25])=[O:24])=[CH:21][CH:20]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[OH:28][CH:29]1[O:48][C@H:47]([CH2:49][OH:50])[C@@H:34]([O:35][C@@H:36]2[O:44][C@H:43]([CH2:45][OH:46])[C@H:41]([OH:42])[C@H:39]([OH:40])[C@H:37]2[OH:38])[C@H:32]([OH:33])[C@H:30]1[OH:31]>O>[OH:28][CH:29]1[O:48][C@H:47]([CH2:49][OH:50])[C@@H:34]([O:35][C@@H:36]2[O:44][C@H:43]([CH2:45][OH:46])[C@H:41]([OH:42])[C@H:39]([OH:40])[C@H:37]2[OH:38])[C@H:32]([OH:33])[C@H:30]1[OH:31].[Na+:1].[CH2:2]([NH:18][C:19]1[CH:20]=[CH:21][C:22]([C:23]([O-:25])=[O:24])=[CH:26][CH:27]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

Participants

4

Reactant 2

HCID 440995(+)-LactoseHCID 23703815Cetaben Sodium2×

Product 1

HCID 131712645HCID 131712645, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent3×

Procedure

A solution of 1.0 g. of p-hexadecylaminobenzoic acid sodium salt and 3.0 g. of lactose in 12.5 ml. of water at 75°-85° C. is frozen quickly by immersion in a -80° C. bath and lyophilized. The resulting solid coprecipitate is pulverized. This coprecipitate is soluble in water at 10 mg./ml. as opposed to p-hexadecylaminobenzoic acid sodium salt, which is soluble in water at 1 mcg./ml.

Sources & evidence

ORD record
ord-363580fc89f247a2bfa35dd624a8d773
Source dataset
uspto-grants-1982_01
Patent number
US04311694

Reaction notes

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