m-Chloroperbenzoic acid → HCID 70552863, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 0.7 g (3.4 mmol) of m-chloroperbenzoic acid (85 percent) in 10 ml of methanol is slowly added at room temperature to a suspension of 1 g (2,3 mmol) of 6-methyl-11-[(4-methyl-1-piperazinyl)acetyl]-2-phenyl-5,6-dihydropyrimido[4,5-b][1,5]benzodiazepin-5-one in 40 ml of methanol. After stirring for 3 hours at 20° C. and filtering, the filtrate is concentrated in vacuo and the residue is purified by chromatography on neutral silica gel using 20:1 chloroform/methanol as the eluant. Yield: 0.5 g (48%).

Provenance & Evidence