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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106068Generated: October 31, 2026

Ammonia → (8S)-7-(3-mercapto-2-methylthio-1-oxopropyl)-1,4-dioxo-7-azaspiro[4.4]nonane-8-carboxylic acid

https://huagongshe.com/reaction/1106068

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant(8S)-7-[3-(Acetylthio)-2-methylthio-1-oxopropyl]-1,4-dioxo-7-azaspiro[4.4]nonane-8-carboxylic acidHCID 56977003—
Product(8S)-7-(3-mercapto-2-methylthio-1-oxopropyl)-1,4-dioxo-7-azaspiro[4.4]nonane-8-carboxylic acidHCID 57148383—

Reaction Steps

The product from part (c) is treated with concentrated ammonia according to the procedure of Example 2 to yield (8S)-7-(3-mercapto-2-methylthio-1-oxopropyl)-1,4-dioxo-7-azaspiro[4.4]nonane-8-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04311697
Source datasetuspto-grants-1982_01
ORD IDord-3b397fe47e5f420eb7f734036e2217ea
Source noteuspto-grants-1982_01