Ammonia → HCID 57061873, compound

HRID 1106074Notes

Reaction equation

HRID 1106074 reaction equation
C([S:4][CH2:5][CH2:6][CH2:7][C:8]([N:10]1[C@H:20]([C:21]([OH:23])=[O:22])[CH2:19][C:12]2([C:16](=[O:17])[CH2:15][CH2:14][C:13]2=[O:18])[CH2:11]1)=[O:9])(=O)C.N>>[SH:4][CH2:5][CH2:6][CH2:7][C:8]([N:10]1[C@H:20]([C:21]([OH:23])=[O:22])[CH2:19][C:12]2([C:16](=[O:17])[CH2:15][CH2:14][C:13]2=[O:18])[CH2:11]1)=[O:9]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22818912HCID 22818912, compound

Product 1

HCID 57061873HCID 57061873, compound

Procedure

The product from part (a) is hydrolyzed with concentrated ammonia according to the procedure of Example 2 to yield (8S)-7-(4-mercapto-1-oxobutyl)-1,4-dioxo-7-azaspiro[4.4]nonane-8-carboxylic acid.

Sources & evidence

ORD record
ord-81938c65df68425cbb6c338e897a4e6b
Source dataset
uspto-grants-1982_01
Patent number
US04311697

Reaction notes

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