Ammonia → HCID 57243243, compound

HRID 1106078Notes

Reaction equation

HRID 1106078 reaction equation
C([S:4][CH2:5][C:6]([CH3:24])([CH3:23])[C:7]([N:9]1[C@H:19]([C:20]([OH:22])=[O:21])[CH2:18][C:11]2([C:15](=[O:16])[CH2:14][CH2:13][C:12]2=[O:17])[CH2:10]1)=[O:8])(=O)C.N>>[SH:4][CH2:5][C:6]([CH3:24])([CH3:23])[C:7]([N:9]1[C@H:19]([C:20]([OH:22])=[O:21])[CH2:18][C:11]2([C:15](=[O:16])[CH2:14][CH2:13][C:12]2=[O:17])[CH2:10]1)=[O:8]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 57275644HCID 57275644, compound

Product 1

HCID 57243243HCID 57243243, compound

Procedure

The product from part (a) is hydrolyzed with concentrated ammonia to yield (8S)-7-(3-mercapto-2,2-dimethyl-1-oxopropyl)-1,4-dioxo-7-azaspiro[4.4]nonane-8-carboxylic acid.

Sources & evidence

ORD record
ord-1cfcf6fe03664273956fb226d13c45d2
Source dataset
uspto-grants-1982_01
Patent number
US04311697

Reaction notes

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