HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[[(4-Methoxy)phenylmethyl]thio]-2-methylthiopropionyl chloride → [8S]-7-[3-[[(4-Methoxy)phenylmethyl]thio]-2-methylthio-1-oxopropyl]-7-aza-1,4-dithiaspiro[4.4]-nonane-8-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[[(4-Methoxy)phenylmethyl]thio]-2-methylthiopropionyl chloride | HCID 54225835 | — |
| Reactant | (8S)-7-(3-mercapto-2-methylthio-1-oxopropyl)-1,4-dioxo-7-azaspiro[4.4]nonane-8-carboxylic acid | HCID 57148383 | — |
| Product | [8S]-7-[3-[[(4-Methoxy)phenylmethyl]thio]-2-methylthio-1-oxopropyl]-7-aza-1,4-dithiaspiro[4.4]-nonane-8-carboxylic acid | HCID 22818909 | — |
Reaction Steps
The 3-[[(4-methoxy)phenylmethyl]thio]-2-methylthiopropionyl chloride from part (a) is reacted with 4,4-ethylenedithio-L-proline according to the procedure of Example 9 (d) to yield [8S]-7-[3-[[(4-methoxy)phenylmethyl]thio]-2-methylthio-1-oxopropyl]-7-aza-1,4-dithiaspiro[4.4]nonane-8-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04311697 |
| Source dataset | uspto-grants-1982_01 |
| ORD ID | ord-1e29d1bd29e54ae78172f163441e9d7b |
| Source note | uspto-grants-1982_01 |