Ammonia → HCID 57006841, compound

HRID 1106085Notes

Reaction equation

C([S:4][CH:5]([CH3:21])[CH2:6][C:7]([N:9]1[CH2:16][C:15]([O:19][CH3:20])([O:17][CH3:18])[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8])(=O)C.N>>[SH:4][CH:5]([CH3:21])[CH2:6][C:7]([N:9]1[CH2:16][C:15]([O:19][CH3:20])([O:17][CH3:18])[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8]

Participants

Reactant 2

HCID 222Ammonia

HCID 57265732HCID 57265732, compound

Product 1

HCID 57006841HCID 57006841, compound

Procedure

The product from part (a) is hydrolyzed with concentrated ammonia according to the procedure of Example 4 to yield (S)-1-(3-mercapto-3-methyl-1-oxopropyl)-4,4-dimethoxy-L-proline.

Sources & evidence

ORD record: ord-e09386ce77f44580a41e28e6eaf00b8c
Source dataset: uspto-grants-1982_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04311697

Reaction notes

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