Dimethylacetamide → HCID 178521179, compound

Participants

Reaction Steps

A suspension of 6.2 g (17 mmol) of the above pyrimidine acid, 4.9 g (30 mmol) of carbonyldiimidazole and 60 ml of N,N-dimethylacetamide is stirred overnight at room temperature. The mixture is diluted with 100 ml of dichloromethane and the solid is filtered, washed with dichloromethane, and dried to give 7.0 g of the title imidazolide; mp 245°-250° C.

Provenance & Evidence