2,6-Dimethylaniline → HCID 13014222, compound

Participants

Reaction Conditions

Reaction Steps

46.7 g (0.2 mole) of ω-bromo-4-chloroacetophenone in 40 ml of ethanol were added to 48.4 g (0.4 mole) of 2,6-dimethylaniline in 40 ml of ethanol and the mixture was warmed to 50° C. for 20 minutes. Thereafter, it was cooled to 0° C. and the crystals which had formed were filtered off and rinsed with a little ethanol. 30 g (55% of theory) of 2,6-dimethyl-N-(4-chlorobenzoylmethyl)-aniline of melting point 82° C. were obtained.

Provenance & Evidence