反应详情

The optical purity of the acid moiety of fenvalerate A was determined as follows: Fenvalerate A was hydrogenated in ethanol using platinum oxide as a catalyst to obtain (S)-2-(4-chlorophenyl)isovaleric acid which was then converted to an acid chloride using thionyl chloride. The acid chloride was converted to the l-menthol ester with l-menthol. The ratio between the two resulting diastereomers was determined by gas chromatography, and the optical purity of the acid moiety was calculated.