HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylpyridine → HCID 178526221, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylpyridine | HCID 7963 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Reactant | HCID 178526220 | HCID 178526220 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 178526221 | HCID 178526221 | — |
Reaction Steps
Under argon, butyl lithium in hexane (8.35 ml, 1.6 M solution) was added to a solution of 4-picoline (1.23 g) in THF (25 ml) at -30° C. slowly over 20 mins. The solution was then stirred at room temperature for 1 hr and anhydrous manganous chloride (1.51 g) added at 0° C. The suspension was stirred for ca. 3/4 hr at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04312874 |
| Source dataset | uspto-grants-1982_01 |
| ORD ID | ord-7aac3c2d17524f229c58fc7cb5509f2d |
| Source note | uspto-grants-1982_01 |