Sodium Hydroxide → HCID 178507701, compound

Participants

Reaction Steps

The solution of 1.9 g of 2-(p-nitrophenyl)-pyrazolo-[4,3-c]-quinolin-3(5H)-one in the mixture of 18.6 ml of 2 N aqueous sodium hydroxide and 75 ml of ethanol is hydrogenated over 0.2 g of platinum oxide at 2.7 atm. for 6 hours. The mixture is filtered, the filtrate evaporated, the residue taken up in water and the solution washed with diethyl ether. The pH thereof is adjusted to about 8.5 by addition of aqueous ammonium chloride, the precipitate collected, washed successively with methanol and diethyl ether and dried, to yield the 2-(p-aminophenyl)-pyrazolo[4,3-c]quinolin-3(5H)-one, showing IR-peaks at 896, 885, 865, 840, 820, 815, 782, 776, 761, 740, 736 and 720 cm-1.

Provenance & Evidence