HCID 13093694, compound → HCID 13093692, compound

Participants

Reaction Steps

The starting material is prepared thus: 2 g if 1-(p-chlorophenyl)-3-(o-nitrophenyl)-4,5-dihydropyrazol-5-one are catalytically hodrogenated in 100 ml of ethanol over 200 mg of 5% platinum on carbon at room temperature and 3 atmospheres. Since the product crystallizes from the mixture as it is formed, the mixture is diluted with dichloromethane to dissolve said crystalline product. It is filtered, the filtrate evaporated, and the dried residue recrystallized from ethanol, affording the 3-(o-aminophenyl)-1-(p-chlorophenyl)-4,5-dihydropyrazol-5-one melting at 199°-201°.

Provenance & Evidence