Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106274Generated: October 31, 2026

1-Chloro-4-(chloromethyl)benzene → 1-(4-Chlorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine

https://huagongshe.com/reaction/1106274

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-(chloromethyl)benzeneHCID 7723—
Reactant1-(2-Hydroxy-3-n-hexadecyloxypropyl)-piperazineHCID 13037790—
Product1-(4-Chlorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazineHCID 13037793—

Reaction Steps

Following the procedure of Example 5, 1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine was reacted with 4-chlorobenzylchloride to form 1-(4-chlorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine, mp 237°-239° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04312877
Source datasetuspto-grants-1982_01
ORD IDord-cd391eb57a33435f8d2ea92134c51fc7
Source noteuspto-grants-1982_01