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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106277Generated: November 2, 2026

4-Fluorobenzyl chloride → 1-(4-Fluorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine

https://huagongshe.com/reaction/1106277

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl chlorideHCID 9602—
Reactant1-(2-Hydroxy-3-n-hexadecyloxypropyl)-piperazineHCID 13037790—
Product1-(4-Fluorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazineHCID 13037797—

Reaction Steps

Following the procedure of Example 5, 1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine was reacted with 4-fluorobenzyl chloride to form 1-(4-fluorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine, mp 242° C. (dec).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04312877
Source datasetuspto-grants-1982_01
ORD IDord-da71262fc8514bbd8f3c17f63a502407
Source noteuspto-grants-1982_01