HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Propylcyclohexanone → 4-[2-(4-Propylcyclohexylidene)ethyl]propylidenecyclohexane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Propylcyclohexanone | HCID 142482 | — |
| Reactant | Triphenyl[2-(4-propylidenecyclohexyl)ethyl]phosphonium bromide | HCID 18787859 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-[2-(4-Propylcyclohexylidene)ethyl]propylidenecyclohexane | HCID 18787855 | — |
Reaction Conditions
| Temperature | -10 °C |
|---|
Reaction Steps
57.0 g of 4-propylcyclohexanone and 25.0 g of triphenyl[2-(4-propylidenecyclohexyl)ethyl]phosphonium bromide were introduced into 150 ml of THF under nitrogen, and the mixture was cooled to -10° C. A solution of 5.61 g of potassium tert-butoxide in 100 ml of THF was then added dropwise with stirring, and the mixture was stirred at RT for a further 2 h. Conventional work-up gave 4-[2-(4-propylcyclohexylidene)ethyl]propylidenecyclohexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06056895 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-9f5a8e42bd594fb3be18f9f2ef963672 |
| Source note | uspto-grants-2000_05 |