HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15524191, compound → 5-Bromo-1,2,3,4-tetrahydro-2-(2-phenylethyl)-7,8-isoquinolinediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15524191 | HCID 15524191 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Bromo-1,2,3,4-tetrahydro-2-(2-phenylethyl)-7,8-isoquinolinediamine | HCID 15524192 | 98% |
Reaction Steps
A solution of the product from Example 9 (0.6 g, 1. mmol) in THF (50 mL) was stirred over RaNi under a hydrogen balloon for 40 mins. The catalyst was filtered off and concentrated under vacuum to give the title compound (0.54 y, 98% yield) as a pink solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06057313 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-4fe338a7fa044226a70ec207d110c49f |
| Source note | uspto-grants-2000_05 |