HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic Acid → HCID 15524196, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic Acid | HCID 971 | — |
| Reactant | 5-Bromo-1,2,3,4-tetrahydro-7-nitro-2-(3-phenylpropyl)-8-isoquinolinamine | HCID 15524194 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 15524196 | HCID 15524196 | 60.3% |
Reaction Steps
A solution of the product from Example 12 (0.98 g, 2.72 mmol) in 3N HCl (35 mL) was treated with oxalic acid (0.36 g, 2.86 mmol) and refluxed for five hours. When cool to room temperatures the precipitate was filtered, suspended in water (70 mL) and basifyed to pH 8. The solids were filtered, and dried to give the title compound (0.68 g, 60%) as a brown solid, mp=288-293° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06057313 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-ebeecbeca3644c59b97b3ab96acdbe55 |
| Source note | uspto-grants-2000_05 |