Hydrochloric Acid → HCID 18788827, compound

Participants

Reaction Steps

13 g of methyl 2-methyl-5-nitro-4-phenylbenzoate were dissolved in 150 ml of MeOH and treated with 10 g of iron powder. A saturated aqueous HCl solution was then slowly added dropwise and the mixture was stirred at RT for 2 hours. The volatile components are removed in vacuo at a maximum temperature of 30° C., 500 ml of a saturated aqueous Na2CO3 solution were added, the iron salts were filtered off and the filtrate was extracted 3 times using 500 ml of EA each time. The organic phase was dried over Na2SO4 and the solvent was removed in vacuo. 10 g of colorless oil were obtained.

Provenance & Evidence