5-Methoxytetralone → HCID 54436782, compound

HRID 1106543Notes

Reaction equation

HRID 1106543 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH2:5][CH2:6][CH2:7][C:8]2=[O:13].C(O[CH:17](OCC)[N:18]([CH3:20])[CH3:19])C>>[CH3:17][N:18]([CH:20]=[C:7]1[CH2:6][CH2:5][C:4]2[C:9](=[CH:10][CH:11]=[CH:12][C:3]=2[O:2][CH3:1])[C:8]1=[O:13])[CH3:19]

Participants

3

Reactant 2

HCID 366205-MethoxytetraloneHCID 70913Dimethylformamide diethylacetal

Product 1

HCID 54436782HCID 54436782, compound

Procedure

The 3,4-dihydro-2-(dimethylaminomethylene)-5-methoxy-1(2H)-naphthalenone starting material was prepared from 5-methoxy-1-tetralone (5.0 g, 28.4 mmol) and N,N-dimethylformamide diethyl acetal (25 g, 170.2 mmol) to give the desired product as brown needles (5.27 g). m.p. 108-110°. MS (ES+) 232 (MH+, 100%).

Sources & evidence

ORD record
ord-f9c943153d8c42159c2c782f8a2f7719
Source dataset
uspto-grants-2000_05
Patent number
US06057329

Reaction notes

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