Dimethylformamide diethylacetal → HCID 54100357, compound

HRID 1106552Notes

Reaction equation

HRID 1106552 reaction equation
[CH2:1]1[CH2:10][C:8](=[O:9])[C:4]2[CH:5]=[CH:6][S:7][C:3]=2[CH2:2]1.C(O[CH:14](OCC)[N:15]([CH3:17])[CH3:16])C>>[CH3:14][N:15]([CH:17]=[C:10]1[CH2:1][CH2:2][C:3]2[S:7][CH:6]=[CH:5][C:4]=2[C:8]1=[O:9])[CH3:16]

Participants

3

Reactant 2

HCID 70913Dimethylformamide diethylacetalHCID 834184,5,6,7-Tetrahydro-4-oxothionaphthene

Product 1

HCID 54100357HCID 54100357, compound

Procedure

The 5-(dimethylaminomethylene)-4-oxo-4,5,6,7-tetrahydrobenzo[b]-thiophene starting material was prepared from 4-keto-4,5,6,7-tetrahydrothianaphthene (5.0 g, 33 mmol) and N,N-dimethylformamide diethyl acetal (15 ml, 87.5 mmol) to give the desired product as large yellow crystals (2.3 g) after recrystallisation from ethyl acetate m.p. 106.9°. MS (ES+) 208 (MH+, 100%).

Sources & evidence

ORD record
ord-1e3acb2291444dbbb21c3ca6d7485856
Source dataset
uspto-grants-2000_05
Patent number
US06057329

Reaction notes

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