HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl vinyl ether → HCID 86755095, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl vinyl ether | HCID 8023 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S)- | HCID 18462 | — |
| Reactant | (R)-(2-Methyloxiran-2-yl)-(4-methanesulfonylphenyl)methanol | HCID 86755096 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86755095 | HCID 86755095 | — |
Reaction Steps
To a solution of the product from Step 4 (7.2 g) and ethylvinyl ether (50 mL) in 200 mL of CH2Cl2 cooled to 0° C. was added 50 mg of camphorsulfonic acid. The reaction mixture was stirred at r.t. for 20 min. and then treated with 1 mL of Et3N, concentrated to give the crude title compound (9 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06057319 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-b773f38fcb4f43b98749622b98b59953 |
| Source note | uspto-grants-2000_05 |