Sodium Hydroxide → HCID 22114233, compound

HRID 1106610Notes

Reaction equation

HRID 1106610 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]=1[O:15][CH3:16])[O:5][CH2:6][C:7]([O:9]CC)=[O:8].[OH-].[Na+]>C1COCC1.CO>[Cl:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]=1[O:15][CH3:16])[O:5][CH2:6][C:7]([OH:9])=[O:8]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22114273HCID 22114273, compound

Product 1

HCID 22114233HCID 22114233, compound

Reagents, catalysts & solvents 1

HCID 21899815MeOH tetrahydrofuranSolvent

Procedure

The above ethyl 3-chloro-4-methoxyphenoxyacetate (700 mg) was hydrolysed with 1M aq. NaOH in THF-MeOH (30 mL, 2:1) to provide the title compound as a white powder.

Sources & evidence

ORD record
ord-84cab8acfcf44850835ca1a7616efab8
Source dataset
uspto-grants-2000_05
Patent number
US06057319

Reaction notes

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